翻訳と辞書 Words near each other ・ Dibrugarh district ・ Dibrugarh Municipal Board ・ Dibrugarh railway station ・ Dibrugarh Rajdhani Express ・ Dibrugarh University ・ Dibrugarh-Bangalore Express ・ Dibrugarh-Chandigarh Express ・ Dibrugarh-Kanyakumari Vivek Express ・ Dibs ・ Dibs (song) ・ Dibs in Search of Self ・ Dibsi Faraj ・ Dibson T. Hoffweiler ・ Dibu 3 ・ Dibu Ojerinde ・ Dibucaine number ・ Dibulla, La Guajira ・ Dibumba I ・ Dibumba II ・ Dibunate ・ Dibutyl ether ・ Dibutyl phthalate ・ Dibutyl sebacate ・ Dibutylamine ・ Dibutylboron trifluoromethanesulfonate ・ Dibutylhexamethylenediamine ・ Dibutylone ・ Dibutyltin dilaurate ・ Dibutyltin oxide ・ Dibutyltryptamine Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Dibucaine number ： ウィキペディア英語版 Dibucaine number Dibucaine, also known as cinchocaine, is an amino amide local anesthetic. When administered to humans intravenously, it is capable of inhibiting the plasma cholinesterase enzyme. ==Metabolism== Plasma cholinesterase is also known as butyrylcholinesterase, in part because once an individual is given butyrylcholine intravenously, the enzyme converts it to the products butyric acid and choline. This tetrameric enzyme is responsible for the metabolism of a number of substances, including amino ester local anesthetics and succinylcholine which it hydrolyses in two stages to succinyl monocholine and choline, then to succinic acid and a second molecule of choline. Dibucaine inhibits normal butyrylcholinesterase activity, reducing the ability to convert butyrylcholine to its byproducts. The extent of the catalysis can be determined by measuring the percentage of butyrylcholine that remains unchanged in the blood of individuals administered a standard dose after dibucaine inhibition challenge in what has been established as the dibucaine number test. Kalow and Genest〔 first described this means of determining butyrylcholinestersase activity in 1957. Typical measurement of dibucaine number in the United States yields values of 80 and above for wild type homozygotes (normal), 40–60 for heterozygotes (atypical), and 20 or less for atypical homozygotes.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Dibucaine number」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.